A gene therapy, patented through the University of California, San Diego (UCSD) and the Department of Veterans Affairs (and licensed to Eikonoklastes Therapeutics), measurably delayed disease onset in humanized mouse and rat models of familial amyotrophic lateral sclerosis (ALS).
After recently receiving approval in Canada, AMX0035 looks to join the US market alongside riluzole and edaravone, the only FDA-approved therapeutics that slow disease progression in ALS.
Wichterle’s unlikely journey from basic scientist to drug developer began when he discovered how to efficiently create functional spinal motor neurons in a laboratory dish from embryonic stem cells.
Ales for ALS was the brainchild of Cheryl Hanses and her husband Mike Smith, a third-generation hop farmer in Yakima, Washington. Hanses’ family has been ravaged over the years by ALS, (amyotrophic lateral sclerosis, commonly known as Lou Gehrig’s disease). Hanses has nine family members who she knows who either died from ALS or are currently battling the disease. Her family has one of the identified mutant genes that causes ALS.
It is the 19th Christmas in July fundraiser the tavern has hosted to raise funds for local nonprofits. This year the recipient will be Hope Loves Company Inc., a Pennington-based nonprofit that supports children and young adults who have family members affected by ALS – amyotrophic lateral sclerosis, commonly known as Lou Gehrig’s disease. It is a horrible degenerative disease that affects the brain and spinal cord and causes a loss of voluntary muscle control that affects movements such as talking, swallowing and walking.
The ALS Association Upstate New York Chapter and Advance Media NY will team up to raise critical funds and awareness for the fight against ALS by participating in the ALS Association’s CEO Soak on Aug. 11 at 1 p.m. at Clinton Square.
In some way, shape or form, we are all list people. Some people are of the pen and paper list variety, others have taken to keeping notes on their phone or online calendar. And even those who would claim to not keep lists probably have an idea of some “to dos” they keep in their head. For ALS caregivers, far too often the last thing on their lists is themselves. So, here’s a list of ALS caregiver “to dos” for their own self-care and wellness.