Funding Opportunities for Clinics
Funding Opportunities for Clinics

Funding Opportunities for Researchers

We invest millions of dollars every year to support cutting-edge research across the translational pipeline from basic science to early-phase clinical trials as well as funding projects focused on other important areas, such as prevention, assistive technology, quality of care, workforce development and research infrastructure.  

Many of our awards are offered annually, but some are one-time only grants. All our programs require a letter of intent (LOI) followed by a full proposal (by invitation only). You can learn more on our Information for Applicants and Awardees page.

Our Requests for Applications

Seed Grants 

Description: These grants fund preliminary ALS research that will support funding applications from other sources for larger scale and more impactful research projects. 
Funding: Up to $50,000 over 1 year
This opportunity has closed.

The Hoffman ALS Clinical Trial Awards Program 

Description: This program supports early- to mid-stage (phase 1 or 2a) interventional clinical trials of novel or repositioned therapeutics for ALS. 
Funding: Up to $1,000,000 over 2–3 years 
This opportunity has closed.

Milton Safenowitz Postdoctoral Fellowship Program

Description: This program supports the development of early career scientists by funding junior postdoctoral fellows doing research of high scientific merit and relevance to ALS. 
Funding: Up to $150,000 over 2 years 
This opportunity has closed. 

The Lawrence and Isabel Barnett Drug Development Program 

Description: This program supports the preclinical development of new or repurposed treatments for ALS. 
Funding: Up to $500,000 over 2 years 
This opportunity has closed.  

Learn About Our Awards and Programs

Additional Funding Opportunities 

2024 Sean M. Healey International Prize for Innovation in ALS 

Funding Organization: Sean M. Healey & AMG Center for ALS  
Description: This global prize celebrates excellence in research for a team of investigators who have catalyzed exceptional discoveries that have led to a transformative advance in therapy development in ALS. 
Prize: $50,000 and travel reimbursement up to $2,500 to attend the International Symposium on ALS/MND 
Nominations Due: July 26, 2024, 5 p.m. ET 

Drs. Ayeez and Shelena Lalji & Family ALS Endowed Award for Innovative Healing 

Funding Organization: Sean M. Healey & AMG Center for ALS  
Description: This annual, global prize recognizes an individual or team for excellence in their transformative scientific discoveries focused on repair and regeneration of neurological function in ALS. 
Available Funding: $40,000 and travel reimbursement up to $2,500 to attend the International Symposium on ALS/MND 
Nominations Due: August 23, 2024, 5 p.m. ET 

Clinical Studies of Orphan Products Addressing Unmet Needs of Rare Diseases (R01) 

Funding Organization: U.S. Food and Drug Administration 
Description: This program funds clinical trials evaluating the efficacy and/or safety of existing products in support of a new indication or change in labeling to address unmet needs in rare diseases or conditions, such as ALS. 
Available Funding: Up to $650,000 per year for four years 
Open Date: August 23, 2024 

Clinical Research Training Scholarship in ALS 

Funding Organizations: The ALS Association and American Brain Foundation in collaboration with the American Academy of Neurology   
Description: This award aims to recognize the importance of good clinical research and to encourage early career investigators in clinical studies in ALS. Recipient must be an AAN member interested in an academic career in neurological research who has completed residency or a Ph.D. no more than five years prior to the beginning of this award (July 1, 2025). 
Available Funding: $65,000 per year for two years, plus a $10,000 per year stipend to support education and research-related costs 
Application Deadline: September 10, 2024 

Richard Olney Clinician Scientist Development Award in ALS 

Funding Organizations: The ALS Association and American Brain Foundation in collaboration with the American Academy of Neurology   
Description: This award recognizes the importance of good clinical research and encourages early career investigators in clinical studies in ALS. Recipient must be an AAN member interested in an academic career in neurologic research who has completed residency or a Ph.D. no more than seven years prior to the beginning of this award (July 1, 2025). 
Available Funding: $75,000 per year for three years, plus a $5,000 per year stipend to support education and research-related costs 
Application Deadline: September 10, 2024 

Clinical Studies of Orphan Products Addressing Unmet Needs of Rare Diseases (R01) 

Funding Organizations: U.S. Food and Drug Administration (FDA) 
Description: The purpose of this opportunity is to fund clinical trials (Phase 1, 2, and/or 3) of products evaluating efficacy and/or safety in support of a new indication or change in labeling to address unmet needs in rare diseases or conditions.
Available Funding: Up to $650,000 per year for up to four years; applicants may request up to an additional $250,000 total costs per year (to a maximum total award cost of $900,000 per year) for innovative and efficient trial approaches.
Application Deadline: October 22, 2024, 11:59 p.m. ET 

Sheila Essey Award for ALS Research 

Funding Organizations: The ALS Association, American Academy of Neurology, and American Brain Foundation 
Description: This award recognizes an individual who has made significant research contributions in the search for the cause, prevention of, and cure for ALS. The criteria being used to determine the recipient include recent major scientific impact, long-term scientific impact, and overall impact to ALS.
Prize: $50,000 to continue ALS research and complimentary registration for the American Academy of Neurology’s 2025 Annual Meeting
Application Deadline: October 31, 2024, 11:59 p.m. CT 

Want to add your funding opportunity to this list? Contact us at ResearchGrants@als.org

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Funding Opportunities for Clinics