Levels of a protein called neurofilament light chain (NfL) in the blood can identify those who might have neurodegenerative diseases such as Down’s syndrome dementia, motor neuron disease (ALS) and frontotemporal dementia, when clinical symptoms are not definitive.
Compared to sporadic or nonfamilial ALS, patients with C90rf72 are thought to have a more progressive disease course. Evidence shows the immune system in disease progression in patients with C90rf72, but little is known about which players are involved.
Researchers identified lifestyle differences among patients with amyotrophic lateral sclerosis (ALS) dependent on chromosome 9 open reading frame 72 (C9orf72) mutational status in a case control study published in Lancet Neurology.
- Submission Supported by Data from the CENTAUR Trial
- CENTAUR Evaluated the Safety and Efficacy of AMX0035 in People with ALS and Demonstrated Statistically Significant Benefit in Function and Survival with Similar Rates of Adverse Events between AMX0035 and Placebo Arms
One day during the first week of spring training back in February, Aaron Nola excused himself from morning pitchers’ stretch and asked manager Joe Girardi for a minute of his time.
Ilkin, who played 14 years on the offensive line for the Steelers from 1980-1993 and spent the last 23 as a broadcaster for the team, announced his decision Thursday.